CpG island DNA methylation plays an important role in regulating gene expression in development and carcinogenesis. We developed a new microarray-based method called methylation amplification DNA chip ...

Microarrays, including genome tiling microarrays, are exceptionally powerful tools for querying diverse genomic features, including mapping gene expression and structure, analyzing polymorphisms, ...

Scientists at the Leibniz Institute of Photonic Technology (Leibniz IPHT) have developed a new microarray-based diagnostic ...

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...

San Diego, Ca. -- Researchers at the University of California, San Diego have used a new strategy to identify differences between non-metastatic and highly metastatic breast cancer cells. The article ...

MicroRNAs (miRNAs) are small, short non-coding RNAs that bind to specific messenger RNAs (mRNAs) and regulate gene expression either by degradation or by translational inhibition of the mRNA. miRNAs ...

Curious about how to detect and characterize tumor-derived biomarkers from liquid biopsy samples? Genomics-based methods now provide access to more molecular data than ever before, delivering cancer ...

Relationship of pro-angiogenic factor Cyr61to colorectal cancer development and prognosis. Background: Microarrays are widely used to study gene expression patterns in cancer. In colorectal cancer, it ...

Two of the critical issues that arise when examining DNA microarray data are (1) determination of which genes best discriminate among the different types of tissue, and (2) characterization of ...

Early Completion of Model-Assisted Designs for Dose-Finding Trials Accurate assessment of a molecular classifier that guides patient care is of paramount importance in precision oncology. Recent years ...

Many recently developed pneumococcal serotyping methods detect the dominant serotype in a laboratory or field sample, but several fail to detect minor serotypes, according to a study published this ...